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CBD to desensitize TRPV1 receptors prior to eating superhots?

J

John1234

So I was blundering around RG again, and came across this. Obviously intended as research for the medical field, but is this something one could exploit? Perhaps someone with access to a CBD dominant strain wants to guinea pig some home-grown experimenting?
 
Non-psychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability
 
Or, more likely, am I off my rocker, deluded by a very basic/laymans understanding of the science involved?
 
 
Not entirely sure how kosher it is to download these articles and repost...? I've a casual disregard of rules that is held by all the coolest kids in school, so I'll probably just keep doing it. To emulate them. I was definitely in the freaks and geeks crowd during that particular phase of life.
 
miguelovic said:
So I was blundering around RG again, and came across this. Obviously intended as research for the medical field, but is this something one could exploit? Perhaps someone with access to a CBD dominant strain wants to guinea pig some home-grown experimenting?
 
Non-psychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability
 
Or, more likely, am I off my rocker, deluded by a very basic/laymans understanding of the science involved?
Click to expand...
So, does Neuronal Hyperexcitability mean something like too much energy? And exposure to cannabinoids cause you to be less excited and more relaxed? Interesting research. :high:
Just playing with you Miguelovic but in my very basic understanding of science it almost sounds like somebody figured a way to earn a grant and get paid for getting high :dance:
 
Hah, I have no idea what the article was originally written for, I just skimmed off what I thought relevant re: desensitizing the receptor that provides the "burning" sensation of peppers.
 
Sounds more like it is related to the sensitivity of epileptics?
 
CBD, if in sufficient quantity will block the psychoactive effects of THC, to my understanding.
 
If anyone would actually go to the trouble of desensitizing their receptors that provide the burning sensation of peppers, I would probably consider them to be at least, a nut, more likely, dangerous.
 
Don't buy this crap.. Eating a reaper will still break you up the next morning..





.. When you go to the toilet :D
 
Topical?
 
 
Mentioning cannabis around here is like naming genitals infront of kindergartners :D
 
There's so many pranks you could play, not to mention dominating/cheating at any competition
 
I smoke CBD rich strains and I eat some pretty hot friggen peppers. Makes sense to me. And better yet the THC helps me forget how bad I just got burned. But there's a good chance I'm a nut or even worse
 
                                DANGEROUS!
 
http://youtu.be/82QRprW_bAY
 
Nothing wrong with being a nut :D Life is more interesting. Some people think my smile is threating or symptomatic of some mental problem. Those people are milksops.
 
I'm still waiting on some mushrooms to experiment with Morouga.
 
My only real concern is I do not like things moving around inside of me, or being reminded of all those organs crammed inside. I usually fast before consuming anything. Having to fire one out is also generally not my idea of a fun time :D
 
Yea I dunno bout that one Mig. Sounds like your trying to cross a diamond with a pearl. It'll either be really great or........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 
What? If you take mushrooms the endorphin flood gate is wide open. Only thing a superhot will do f up your high. My guess anyway, or you die.
 
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