I found this article recently and it refreshed my memory from soil science class 35 years ago.
Thought I'd share
Understanding Antagonistic and Synergistic Nutrient Interactions in Soil to Increase Yield
vlsci.com
Thought I'd share
Understanding Antagonistic and Synergistic Nutrient Interactions in Soil to Increase Yield

Antagonistic and Synergistic Nutrient Interactions in Soil | Verdesian
In the quest for increased yield, itβs essential to understand how different nutrients interact in soil to improve its overall fertility. Learn more here!

What is a Synergistic Nutrient Interaction?
A synergistic nutrient interaction means the interaction between the two nutrients results in an increased yield response that is more than what would be expected of the response to each nutrient individually.
What is an Antagonistic Nutrient Interaction?
When the yield from the combined interaction of two nutrients is less than what would be expected from individual applications, it is called an antagonistic response. In both cases, the interaction between the nutrients affects the amount of nutrients available for uptake and use by the plants.
Most antagonistic reactions were between micronutrients such as Zn, copper (Cu), iron (Fe), calcium (Ca), and magnesium (Mg). These are all cations, or positively charged molecules or atoms. One theory for this negative interaction is that these nutrients compete for the same nutrient transport pathways in plant roots. Cations and anions (negatively charged molecules or atoms) bind to different transport proteins. If all the cation-transporting proteins are already bound to Zn, for example, Cu cannot be absorbed. One strategy to avoid this problem might be to apply one of these nutrients via a different route such as foliar fertilization.