Don't see why they wouldn't work, but you'll have a sh!t tonne of variation in each of the original two crosses, as most of the parents are crosses themselves, so a lot of mixed genetics, and then, once you finally get each of them under control, you put them together and it becomes a case of out of the genetic frying-pan and into the genetic fire.
Sounds great!
You'll be able to "create" a whole range of different "varieties", there will be enough variation in pod shape, size, colour, heat, plant growth patterns, you'll be able to furnish an entire grow with just the products of this experiment!
If you're up for it, you're gonna have a ball! If you do go ahead, you should start a glog on here, I for one would be very interested to follow!
And a tip for ya: As NECM said, you're looking at 16 years. However, if you use an indoor set-up, you could halve that time period. Or if you grow them
really quick, say, 5 months from sowing to harvesting first pod, it would only take 6 years and 8 months (ish) for the full 16 generations. But that's highly unlikely
AND......
You'd be hard pushed to find enough indoor space to grow out a large portion of the variation between phenos. Because we're talking
a lot of space. Like I said, a full grow.
TL;DR Cross should work, you'll have a lot of different phenos to have fun with, and if you have a sh!t tonne of indoor space, you could do it in 8 years. + You should do a glog for it.
Good Luck, TBG.