I've risen a motorcycle 1000 miles in a day. Now that is brutal. A car not as bad. 14-15 hours depending on how often you stop. I try and time it so I'm not in a city at rush hour traffic. That saves time. Be safe. A good nights sleep and leaving early is the only way. It will literally be all day.
My max thus far is about ~800 miles. I drive from Chicago-SWFL usually around once a year, but usually have company part of the way at least and my dogs are with me. This drive is Chicago-Denver. Driving to FL I pass all the boring stuff first and the last 8 hrs is excitements and palm trees. Driving to CO I'm worried about what is supposed to be the most boring stretch of road in America, straight across Nebraska. I'm worried 1000 solo will be a bit taxing but flight+bags+rental...