shame on you ! lolD3monic said:
staring you right in the brown eye
shame on you ! lolD3monic said:
staring you right in the brown eye
TRPV1 said:through a kinase cascade that in turn activates a calcineurin phosphatase enzyme that strips key phosphate groups on TRPV1 thereby inhibiting its function.
TRPV1 said:This is absolutely a real phenomena and it has a biochemical basis related to the TRPV1 receptor. It's also the reason the people use capsaicin for pain management since small levels of agonists such as capsaicin can desensitize the receptor and therefore make it less likely to activate. When it's activated, the TRPV1 receptor causes an influx of cations which stimulates peripheral neurons to produce a burning sensation. Capsaicin exposure produces a calcium response through a kinase cascade that in turn activates a calcineurin phosphatase enzyme that strips key phosphate groups on TRPV1 thereby inhibiting its function.
kim k .... is that you ?The Hot Pepper said: