The misinformation about this is RAMPANT in Latin America. Heart-breaking.
https://www.nature.com/articles/d41586-020-02958-2#ref-CR2
Unbiased article talking about ivermectin's potential. Notice trial sizes. Notice the researchers saying evidence is not there to prescribe.
Notice reference #2 within which dosage is discussed. This is the kicker. That article is worth a read if you want to dig deeper into ivermectins potential or lack thereof. This quotes directly from :
https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bcp.14476
"While the findings by Caly and colleagues provide some promise, several pharmacokinetic factors limit the immediate translation of their findings, and there is no evidence that the 5μM concentration of ivermectin used by Caly and colleagues in their in vitro SARS‐CoV‐2 experiment, can be achieved in vivo. First, the pharmacokinetics of ivermectin in humans is well described,
3-
5 and even with the highest reported dose of approximately 1700 μg/kg (i.e., 8.5 times the FDA‐approved dose of 200 μg/kg), the maximum plasma concentration was only 0.28μM.
5 Second, 93% of ivermectin is bound to plasma proteins that limit its cellular uptake by endothelial cells.
6 Considering both the total plasma concentration and protein binding, the free plasma concentration of ivermectin would be 250 times lower than the concentration required to reduce viral replication of SARS‐CoV‐2 in vitro (Figure
1). Third, whilst there is no data on the tissue penetration of ivermectin in human lungs, the total concentration of ivermectin in calves injected with 200 μg/kg reached only 100 ng/g (approx. 0.1μM) in lung tissue, which suggests that its accumulation would not be sufficient to achieve the antiviral effect with conventional doses.
7 Although high doses of ivermectin in adults or children are well tolerated,
5,
8 the clinical effects of ivermectin at a concentration of 5μM range are unknown and may be associated with toxicity. Consequently, ivermectin has in vitro activity against SARS‐CoV‐2, but this effect is unlikely to be observed in vivo using current dosing."
tl;dr - you can take gallons of it but it wont get into high enough concentrations in the right places (LUNGS) to affect SARS COV 2
nature is quite well-know, trusted, unbiased
