CaneDog
eXtreme
I've seen that happen with the tips before, but I don't know about direct cause or a quick solution. Sometimes the cause and effect of these types of conditions can get muddled. It could be fungal. I don't think it's leaf spot per se. In the earlier pictures there was some necrosis at the leaf tips and margins. The grayness may be simply dead leaf tissue absorbing the fungicide or perhaps there's fungus in the leaf tissue that's now dying.
The more I think about it and reflect on similar plant problems I've had before (and having eliminating some early thoughts after hearing more about your setup) I suspect the problems are ultimately coming from issues with the roots/media. This could have started some time back, with you seeing the results of it more recently. I've done media changes before in these situations with successful results. It's a big step, but it gives the plant a solid footing and strength to fight conditions that might have taken hold while the plant was weakened.
Wish I had something better for you. It's no fun having these kinds of hassles in your grow.
The more I think about it and reflect on similar plant problems I've had before (and having eliminating some early thoughts after hearing more about your setup) I suspect the problems are ultimately coming from issues with the roots/media. This could have started some time back, with you seeing the results of it more recently. I've done media changes before in these situations with successful results. It's a big step, but it gives the plant a solid footing and strength to fight conditions that might have taken hold while the plant was weakened.
Wish I had something better for you. It's no fun having these kinds of hassles in your grow.