I'm not positive about liquid smoke, but this brings up something Ive been thinking about. I also want to try making a smoky flavored sauce, but I was going to actually smoke some habs for 3-4 hours, then ferment them. The problem is, smoking is a method of preservation. Some of the chemicals that are infused during smoking will slow putrefaction, which for most things is a good thing, but having anti-microbial properties, it could be bad when it comes to fermentation. Ive read of people fermenting smoked peppers, but I wonder with how much success. With liquid smoke, I dont think it would have any effect on the fermentation process since its just mimicking the smoke flavor.