I'm on Cloud Cuckoo right now. I bought a 1250 watt ceramic heater (max usage, 1200 watts without the humidifier) and stuck it in the building this evening. Keep in mind, I still have enough air leaks to make a sieve look watertight, but it is 37 degrees outside and 56 inside.
Hopefully, I'm being realistic...
I still need to add a layer of IR film and some Mylar to the inside, as well as fill in some air leaks with caulking and add weatherstripping around the door. Then on the outside, use my $17 roll of perfectly clear, six-mil vinyl plastic to cover some windows. All of this should increase my heat retention - at a minimum - 40 percent. That would, in essence, mean than the outdoor temps can drop to about 20-22 degrees before I need to use any supplemental heat.
Lighting is another concern, at least in the future. To make is simple, I need at least 30,000 lux hitting the plant canopy on the shortest day of the year. Today, it was partly sunny and I was collecting about 40,000 lux, but that would translate to 35,000+ with the IR film.
One other aspect, (at the least - there are probably more!) is the CO2 level. Plants need that gas and in the middle of winter, inside a sealed GH, it gets depleted. I guess I could get a group together, have a shouting matching daily, and add enough. Or buy a CO2 generator (which isn't cheap). But, there is an easy, inexpensive way (at least according to Google) to create carbon dioxide - take some water, put sugar in it and add some yeast.
I don't know how well this will work, but my GH is pretty ghetto so far so why stop!
Mike